Spatial Transcriptomics

Spatial Transcriptomics Data Analysis

We provide expert interpretation of spatial transcriptomics (e.g., 10x Visium, NanoString GeoMx, Xenium, MERFISH, RNAscope) in the context of histopathologic features,  lesions, progressive grades of early neoplastic lesions, and toxicology:

• Integration of spatial gene expression data with traditional H&E and IHC findings

• Identification of spatially resolved molecular signatures of toxicity, inflammation, or therapeutic response

• Mapping of cell-type-specific gene expression within tissue microenvironments

• Correlation of spatial transcriptomic patterns with morphologic lesions

• Mechanistic investigation of target engagement, off-target effects, and disease progression

• Visualization and reporting of spatial data for regulatory submissions and scientific publications

This multimodal approach allows us to move beyond “what” happened in a tissue to “where” and “why” molecular changes are occurring — delivering significantly richer scientific insights.